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smac mimetic azd5582  (SMAC Corp)

 
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    SMAC Corp smac mimetic azd5582
    Smac Mimetic Azd5582, supplied by SMAC Corp, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/smac mimetic azd5582/product/SMAC Corp
    Average 90 stars, based on 1 article reviews
    smac mimetic azd5582 - by Bioz Stars, 2026-03
    90/100 stars

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    Direct apoptotic pathway targeting agents in preclinical GBM

    Journal: Cellular Oncology (Dordrecht, Netherlands)

    Article Title: Cell death in glioblastoma and the central nervous system

    doi: 10.1007/s13402-024-01007-8

    Figure Lengend Snippet: Direct apoptotic pathway targeting agents in preclinical GBM

    Article Snippet: U87MG (H, Imm) GSCs (H, P) , Smac Mimetic : AZD5582 (D) SM-164 (D) encapsulated in liposomes grafted with rabies virus glycoprotein and lactoferrin , Targets : cIAP1, cIAP2, XIAP , , • Liposome encasing improved BBB crossing capacity of Smac mimetics • Both tested Smac mimetics induced significant apoptosis of tested GBM cells , [ ] .

    Techniques: Inhibition, Ex Vivo, Expressing, In Vivo, Knockdown, Mouse Assay, Phospho-proteomics, In Vitro, Activity Assay, Irradiation, Activation Assay, Over Expression, Liposomes, Virus